San Blas' neighborhood is to few blocks from the main Square, it is a well-known neighborhood of the artisans. In the church of the place its famous and symbolic pulpit, beautifully had carved almost for 400 years in wood of a single piece. Near the church shops and artists' stores and artisans are developed. The most famous artisans of Cusco are the Mendívil, creators of the multicolored ones and emblematics archangels of long necks, facts in pasta and wood and known worldwide. Also, other families of artisans of San Blas, of same prestige, are the Olave and Merida; the shops of Aguayo, Aguilar, Álvarez, Segovia, Saloma and Gutiérrez, among others.
San Blas' neighborhood is today a downtown neighborhood due to the urban growth of the Cusco; San Blas is known as the "District of the Artists", with the narrow and gnarled streets.
In the Incan times it was one of the most important districts in the Cusco and their name was "T'oqo-kachi" (T'oqo = hollow; kachi = salt). As other districts it was inhabited by the Quechua nobility.
San Blas is a neighborhood of special attractiveness and personality. Their construction and their streets make of him a space of world attraction. It is to only two blocks of the Aucaypata Square, is easy to arrive following San Blas' hill down the street Hatun Rumiyoc. It is celebrated also for their chicherías. On Saturdays there are fairs of crafts.
In San Blas' square there is a church that is believed that it was built on an Inca Sanctuary consecrated to the cult of the "Illapa" (God of the thunder, lightning and ray). Probably, it was opened for first time in 1,544 for the second Bishop Juan Solano. Although some other versions say that it was open after 1559 for the Viceroy Andrés Hurtado of Mendoza's order. It had supported the earthquakes in 1650 and 1950 soon after that it was reinforced partially with stone walls.